1. Signaling Pathways
  2. Epigenetics
  3. Histone Demethylase
  4. Histone Demethylase Inhibitors

Histone Demethylase Inhibitors

KDM1/LSD1

KDM2

KDM3

KDM4

KDM5

KDM6

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Histone Demethylase Inhibitors & Antagonists
Product Name KDM1/LSD1 KDM2 KDM3 KDM4 KDM5 KDM6 Purity
GSK-J4          
KDM6
99.64%
IOX1  
KDM2
KDM3
KDM4
 
KDM6
99.72%
GSK2879552
KDM1/LSD1
          99.75%
LSD1/HDAC6-IN-2
LSD1, IC50: 5 nM
          99.66%
LSD1-IN-31
LSD1
         
LSD1-IN-34
LSD1, IC50: 4.51 nM
         
CPI-455        
KDM5
  98.95%
JIB-04      
KDM4
KDM5
KDM6
98.29%
GSK-J1          
KDM6
99.94%
QC6352      
KDM4A, IC50: 104 nM
KDM4B, IC50: 56 nM
KDM4C, IC50: 35 nM
KDM4D, IC50: 104 nM
KDM5B, IC50: 750 nM
  99.48%
Tranylcypromine hemisulfate
KDM1/LSD1
          99.94%
KDM5-C70        
KDM5
 
SP2509
KDM1/LSD1
          99.90%
Seclidemstat
KDM1/LSD1
          99.77%
GSK-J4 hydrochloride          
KDM6
98.83%
Pulrodemstat benzenesulfonate
KDM1/LSD1
          99.12%
NCGC00244536      
KDM4
    99.58%
GSK467        
KDM5, Ki: 10 nM
KDM5, IC50: 26 nM
  99.55%
AS8351        
KDM5
  99.19%
KDOAM-25 citrate        
KDM5
  98.11%
Daminozide  
KDM2
        99.79%
ML324      
KDM4
    98.54%
Bomedemstat hydrochloride
KDM1/LSD1
          99.94%
KDM5A-IN-1        
KDM5
  99.80%
PFI-90    
KDM3
      99.86%
KDM2A/7A-IN-1  
KDM2
        99.94%
KDM5-IN-1        
KDM5
  99.87%
Bomedemstat dihydrochloride
KDM1/LSD1
          99.55%
TK-129        
KDM5, IC50: 44 nM
  ≥98.0%
PBIT        
KDM5
  99.46%
GSK 690 Hydrochloride
KDM1/LSD1
          98.58%
S2101
KDM1/LSD1
          99.73%
KDM4C-IN-1      
KDM4
    98.99%
YUKA1        
KDM5
  99.56%
INCB059872 dihydrochloride
KDM1/LSD1
          99.18%
KDM2B-IN-4  
KDM2
        99.59%
JQKD82 trihydrochloride        
KDM5
  99.94%
DDP-38003 dihydrochloride
KDM1/LSD1
          98.22%
HDAC6-IN-3
KDM1/LSD1
          ≥98.0%
LSD1-IN-30
LSD1, IC50: 0.291 μM
          99.03%
CBB1007 trihydrochloride
KDM1/LSD1
         
Iadademstat
LSD1
         
INCB059872
KDM1/LSD1
          98.06%
KDM4-IN-2      
KDM4
    98.29%
CBB1007 hydrochloride
KDM1/LSD1
          ≥98.0%
LSD1-IN-5
KDM1/LSD1
         
LSD1-IN-6
KDM1/LSD1
         
CPI-455 hydrochloride        
KDM5
 
LSD1/HDAC6-IN-1
KDM1/LSD1
         
LSD1-IN-13 hydrochloride
KDM1/LSD1
         
MC2652
KDM1/LSD1
         
KDM4-IN-4      
KDM4A-Tudor domain, Ki: 80 μM
   
HSP90/LSD1-IN-1
LSD1
         
LSD1-UM-109
LSD1, IC50: 3.1 nM
         
S1427
KDM1/LSD1
         
LSD1-IN-23
KDM1/LSD1, IC50: 0.58 μM
         
LSD1/2-IN-4
KDM1/LSD1
         
NCL1
LSD1, IC50: 2.5 ± 0.5 μM
         
cis-4-Br-2,5-F2-PCPA
KDM1/LSD1
         
KDM1/CDK1-IN-1
KDM1/LSD1
         
LSD1-IN-26
LSD1, IC50: 25.3 ± 1.4 nM
         
LSD1-IN-21
LSD1, IC50: 0.956 μM
         
KDM5-C49        
KDM5
 
LSD1-IN-35
LSD1
         
LSD1-IN-18
KDM1/LSD1
         
LSD1-IN-25
LSD1, IC50: 46 nM
LSD1, Ki: 30.3 nM
         
(1S,2R)-Tranylcypromine hydrochloride
KDM1/LSD1
         
Arborinine
LSD1
         
LSD1-IN-22
KDM1/LSD1
         
LSD1-IN-19
KDM1/LSD1
         
LSD1/2-IN-3
KDM1/LSD1
         
Tranylcypromine-d5 hydrochloride
KDM1/LSD1
         
LSD1/HDAC-IN-1
LSD1, IC50: 0.571 μM
         
JQKD82        
KDM5
 
LSD1/ER-IN-1
KDM1/LSD1
         
LSD1-IN-36
LSD1, IC50: 0.8 nM
         
CBB1003 hydrochloride
KDM1/LSD1
         
GSK-J1 lithium salt          
KDM6
98.26%